Immune cells in the brain could be targets for obesity treatment

Fat-rich diets cause microglia – immune cells that live in the brain and spinal cord – to trigger overeating and weight gain in mice, a new study shows.

Changing diet to unmask cancer vulnerabilities and reduce cancer risk

Many recent studies showed that calorie restrictions reduce the incidence of cancer, whereas high-calorie diets cause obesity and diabetes, both of which increase the risk of developing cancers.

Western diet exacerbates sepsis, mouse study suggests

High-fat diets cause a dramatic immune system overreaction to sepsis, a condition of systemic bacterial infection. An experimental study in mice has shown that a diet high in saturated fat, sugars and cholesterol greatly exaggerates the inflammatory response to sepsis.